Ongoing monitoring of blood counts, liver and kidney function is also required. Prescribed for Acute Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Rheumatoid Arthritis, Psoriatic Arthritis, Solid Tumors, Small Cell Lung Cancer, Systemic Sclerosis, Neoplastic Diseases, Trophoblastic Disease, Osteosarcoma, Non-Small Cell Lung Cancer, Non-Hodgkin's Lymphoma, Psoriasis, Mycosis Fungoides, Dermatomyositis, Breast Cancer, Choriocarcinoma, Meningeal Leukemia, Graft-versus-host disease, Head and Neck Cancer, Juvenile Idiopathic Arthritis, Lymphoma. Hydroxychloroquine dmard Plaquenil standard of care optometry May 28, 2016 I have been diagnosed with Limited Scleroderma. My choices are Methotrexate, Plaquenil or Sulfasalzine Azulfidine. I researched them and determined Plaquenil would be my last choice, although it was his first, because I already have lattice degeneration of the retina in both eyes and one of the potential side effects is retinal problems. Hi there. Sulphasalasine was helpful in my case but took 12 weeks to kick in. After a while it wasn't as effective and I too was prescribed methotrexate alongside. The side effects of the methotrexate for me were horrendous chronic chest infections and I'm now asthmatic as a result. I've been taking plaquenil, methotrexate and sulfasalazine for many years now. I was terrified to take mtx in the beginning, so I understand why you'd like to put that off for now. I did the same thing and tried plaquenil first. " Prescribed for Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention, Rheumatoid Arthritis, Systemic Lupus Erythematosus. May also be prescribed off label for Bladder Cancer, Acute Nonlymphocytic Leukemia, Soft Tissue Sarcoma, Scleroderma, Pityriasis rubra pilaris, Pemphigus, Pemphigoid, Pancreatic Cancer, Ovarian Cancer, Mantle Cell Lymphoma, Brain Tumor, Bullous Pemphigoid, Cervical Cancer, Cogan's Syndrome, Colorectal Cancer, Ectopic Pregnancy, Eczema, Esophageal Carcinoma, Gastric Cancer, Hodgkin's Lymphoma, Uveitis. Methotrexate plaquenil sulfasalazine REFERENCES - UpToDate, Combination hydroxychloroquine and sulfasalazine - HealthUnlocked Hydroxychloroquine muscle toxicityAtorvaquone vs chloroquineHydroxychloroquine sulfate and pregnancyHydroxychloroquine for leg crampsHydroxychloroquine 200 mg t Original Article from The New England Journal of Medicine — Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications Treatment of Rheumatoid Arthritis with Methotrexate Alone.. Taking plaquenil and sulfasalazine Arthritis Information. DMARDs A Treatment Option for RA Everyday Health. The most common DMARDs are methotrexate, sulfasalazine, hydroxychloroquine, and leflunomide. Less frequently used medications include gold salts, azathioprine, and cyclosporine. Methotrexate — Methotrexate was originally used as a chemotherapy treatment for cancer. Conventional DMARDs that have been paired with methotrexate include sulfasalazine, hydroxychloroquine, cyclosporine, leflunomide and azathioprine. Although studies of these combinations have shown differing levels of benefit, the combinations of methotrexate plus leflunomide and methotrexate plus sulfasalazine are among the most effective. Hi, new to this. I was officially diagnosed with RA today and they doctor recommended these two for treatment methotrexate and sulfasalazine. She suggested methotrexate as it seems to be the best. But I am terrified, and I mean TERRIFIED, of the side effects of both.