I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Hydroxychloroquine with or without food Is plaquenil still manufactured Receptor tyrosine kinase dengue virus chloroquine What next if plaquenil doesn't work? Support Forums. Plaquenil made me sick, so I can't take it either, but there are other medicine out there. I know it is scary but anything to stop the pain and misfunction of not being able to use my hands or move my knees or not have my ankles cave out and fall. Can you stop Plaquenil cold turkey" answer - YES. My rheumy told me to take time out on it for a month once. I really don't know why because he only told me to do it the once and I've been on it for six years now He said to give the system a rest for a moth and siad in his experience the disease seemed to be less active in January - so to do. If you don't have to, don't stop your plaquenil. I stopped taking the plaquenil the beginning of December. It doesn't agree with my stomach I take it with meals too. And since I hadn't had a miraculous recovery the 6 months I'd been on it, I didn't think there was any harm in stopping it. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Can u stop taking plaquenil Treating Lupus with Anti-Malarial Drugs Johns Hopkins., Can you quit plaquenil cold turkey, or have to wean Plaquenil sun allergyPlaquenil usesDdo you have to stop plaquenil slowlyMap of malaria regions chloroquine resistance I have noticed an improvement but it's very little. I have 2 days a week, after my MTX, where I'm just sick. I can't do anything. I've been on the MTX now for about a month and when I see my rheumy in 2 weeks I'm going to see if I can try something else or stop taking it. I don't know if the plaq or MTX or prednisone is what's helping. PLAQUENIL" Rheumatoid Arthritis Community - Support Group. Stopping plaquenil. DailyStrength. What happens if I stop taking plaquenil.. Stop taking the medicine and call your doctor if your symptoms worsen or don't improve. Plaquenil and Children Plaquenil can be dangerous to children, who are particularly sensitive to the drug. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Aug 28, 2012 How long does it take for imuran and plaquenil hydroxychloroquine to completely leave your system if you stop them after taking thrm for 1 month. Dr. Stated plaquenil hydroxychloroquine could also be the reason for my vertigo - could vertigo really start 8 months after taking it? I don't want to stop this drug.