Pharmacodynamics of chloroquine

Discussion in 'Online Canadian Pharmacy' started by Morfik, 19-Mar-2020.

  1. Rtemka Guest

    Pharmacodynamics of chloroquine


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Chloroquine overdose is a life-threatening emergency and should be managed with cardio-respiratory and hemodynamic support, monitoring of potassium along with management of arrhythmias and convulsions, as necessary. A patient who survives the acute phase and is asymptomatic should be closely observed until all clinical features of toxicity resolve. Chloroquine works best when you take it on a regular schedule. For example, if you are taking it once a week to prevent malaria, it is best to take it on the same day of each week. Make sure that you do not miss any doses. If you have any questions about this, check with your doctor. A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Pharmacodynamics of chloroquine

    Chloroquine MedlinePlus Drug Information, Chloroquine Oral Route Proper Use - Mayo Clinic

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  7. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat.

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    Pharmacodynamics PPT 1. PHARMACODYNAMICS 2. • In Greek Pharmacon = Drug Dynamics = Action/Power It covers all the aspects relating to “What a drug does to the body” Mechanism of action 3. • Action How and Where the effect is produced is called as Action. • Effect The type of response producing by drug. 4. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite.

     
  8. Dank0 XenForo Moderator

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Compare Plaquenil vs Chloroquine - Hydroxychloroquine - Wikipedia Plaquenil Hydroxychloroquine - Side Effects, Dosage.
     
  9. [email protected] Well-Known Member

    Selected from data included with permission and copyrighted by First Databank, Inc. Plaquenil hydroxychloroquine sulfate dose, indications, adverse. Plaquenil - FDA prescribing information, side effects and uses Hydroxychloroquine Plaquenil
     
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