It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Plaquenil cost assistance Plaquenil hydroxychloroquine hyperpigmentation When phenothiazine medications, certain beta blockers, or certain parasite medicines are taken together with Plaquenil, interactions can occur that may affect the drug levels in your blood. This could increase your risk for side effects or decrease the effectiveness of the medicines. There are several drugs now that you can take instead of the plaquenil. these type of drugs they have now work in a different way then the methotrexate and plaquenil. most of these drugs you will still take the methotrexate. Lawchick my name is chellety and yes i have had horrbile side effects with the plaquenil they say it is suppose to be the best medication you can use for lupus but i was getting symptoms of that of a diabetes patient like gout in my toe, it was horrible pain and burning OMG, sounds weird but i stop taking the plaquenil and stuck to predisone. Hydroxychloroquine comes as a tablet to take by mouth. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Another medication that can be taken with plaquenil Hydroxychloroquine Plaquenil Side Effects & Dosage for., Is there a drug that I can take to replace plaquenil? Can plaquenil cause sun sensitivity Safe Medication. Acetaminophen, used for pain relief, fevers and cold, is not in the NSAID category like Celebrex. It can be easily found in generic form or under the brand names Tylenol, Actamen or Feverall. Taking it in combination with Celebrex is safe and effective. Can You Take Other Pain Meds Along With Celebrex.. Had to stop taking Plaquenil -. Plaquenil Oral Uses, Side Effects, Interactions.. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Quinacrine can be used together with either Plaquenil or its stronger version Aralen chloroquine for a highly effective combination as the two work together each enhancing the effects of the other. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others.