Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine best time to take Long term side effects of plaquenil for rheumatoid arthritis Patients with lupus, especially those on immunosuppresive medications are prone to post operative infections, including surgical incision infections, sepsis etc. Usually, imuran and cellcept need to be held for at least a week before surgery and resumed a week or so after surgery depending on the overall situations. Call your doctor right away if you start to have a cough that won't go away, weight loss, night sweats, fever, chills, or flu-like symptoms, such as a runny or stuffy nose, headache, blurred vision, or feeling generally ill. These may be signs that you have an infection. Serious skin reactions can occur with this medicine. Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and weight loss surgery Want to know good stuff about plaquenil - HealthBoards, Sulfasalazine Oral Route Precautions - Mayo Clinic Chloroquine antibody Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Rx Side Effects New Plaquenil Guidelines and More - American.. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Plaquenil Uses, Dosage & Side Effects -. Ocular Surgery News. yet some patients still experience permanent vision loss resulting from hydroxychloroquine retinopathy due to improper dosing of the drug. “Plaquenil comes in 200 mg. I had quite a bit of hair loss for about 8 months on Plaquenil, 400 mg per day. I did have extremely thick hair almost to my waist. I ended up getting it cut several months ago to just under my shoulders. About the time I got it cut, the hair loss slowed down considerably. Maybe the weight was contributing to how much was falling out? After surgery we observed no loss of pulmonary domain, no oxygen desaturation, no supplemental oxygen need, early ambulation, no infection, no dehiscence, and no ileus. Within six months, the patient remained healed until, after minor activity, she felt a tearing in the pubic area and presented with a new suprapubic hernia.