Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil prescribed by rheumatologist cut in half Plaquenil for ovarian cancer Plaquenil trouble swallowing Hydroxychloroquine retinal toxicity oct When cut, too much of the drug can be released at once and cause a reaction or side effects. When prescribed 300 mg. daily, you should alternate one tablet one day with two the next. I've been on Plaquenil for almost four years now and it's helped me a lot. Summary Fatigue is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. Sep 13, 2019 Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil side effects tired Plaquenil Hydroxychloroquine - Side Effects, Dosage., Will you have Fatigue with Plaquenil - eHealthMe Can you take plaquenil and cialis together Plaquenil does relieve much of the fatigue. As for the joint pain, still a problem. Yes, depression is an issue, still is. The form of meditation I practice is called Mindfulness Based Stress Reduction and daily practicing helps relieve the symptoms of depression. Plaquenil and Tiredness - Reviews. Plaquenil Side Effects Common, Severe, Long Term -. Is extreme fatigue a side effect of Plaquenil - NRAS. Aug 14, 2017 Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Side effects In some people, HCQ may cause gastrointestinal problems, such as nausea, vomiting, upset stomach, cramps, or diarrhea. These may occur for the first few days a person takes the drug while the body adjusts to the medication. Jan 30, 2018 Hi, I've been taking Plaquenil for many years now and have never experienced any side effects or long term effects. But headache is listed as one of the "mild adverse effects". I would suggest that you try to split the dose as suggested. I've always taken 1 in the AM & 1 at night.