Diuretics are medicines that are often used to treat high blood pressure. There are different types of diuretic, but the type most commonly used to treat high blood pressure are called “thiazide” diuretics. Most of these medicines have names that end in “ide”. Diuretics are sometimes called ‘water tablets’ because they can cause you to pass more urine than usual. They work on your kidneys by increasing the amount of salt and water that comes out through your urine. Too much salt can cause extra fluid to build up in your blood vessels, raising your blood pressure. Diuretics lower your blood pressure by flushing salt out of your body, taking this unwanted extra fluid with it. , loop diuretics are are also indicated for lowering elevated blood pressure. We asked to what degree this drug class lowers blood pressure, whether individual drugs within the class produce different effects, and what the estimate of harms is associated with this class of drugs. We searched the available scientific literature to find all the trials that had addressed these questions. We found 9 trials studying the blood pressure-lowering ability of 5 different loop diuretics (furosemide, cicletanine, piretanide, indacrinone and etozolin) in 460 participants. The blood pressure-lowering effect was modest, with systolic pressure lowered by 8 mm Hg and diastolic pressure by 4 mm Hg. No loop diuretic drug appears to be any better or worse than others in terms of blood pressure-lowering ability. Due to lack of reporting and the short duration of included trials, this , the systolic/diastolic blood pressure-lowering effect of loop diuretics is -8/-4 mm Hg, which is likely an overestimate. 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It's also sometimes used to help you pee when your kidneys aren't working properly. Diuretics are sometimes called "water pills/tablets" because they make you pee more. It comes as tablets and as a liquid that you swallow. It can also be given by injection, but this is usually only done in hospital. Furosemide sometimes comes mixed with other diuretics or potassium. It's usual to take furosemide once a day in the morning. Furosemide (Lasix), a strong diuretic, may be prescribed to treat high blood pressure (hypertension) if your current medications aren't working well. Furosemide stimulates your body to produce more urine so that it can be excreted. Less fluid in the body means less blood volume for your body to push through your cardiovascular system, which brings about a drop in blood pressure. Be careful not to stand up too quickly if you're taking furosemide, which also can cause your blood pressure to drop. 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Dosage is determined by the patient's physician and varies according to how much fluid and how fast the fluid should be removed. Patients with poor renal function usually require higher doses; doses in children are weight-based. Lasix may also be used with antihypertensive drugs to control high blood pressure hypertension. Aldactone is also used to reduce edema caused by certain patients with hyperaldosteronism. Lasix and Aldactone belong to different drug classes. Lasix is an anthranilic acid derivative used as a strong.