Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Lysosomal degradation inhibitor chloroquine Lupus medication hydroxychloroquine side effects Dec 04, 2014 Hydroxychloroquine HCQ is an anti-malarial medication that has in recent times been utilized as treatment for a variety of autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, and other inflammatory and dermatologic conditions. Chloroquine is a potent drug used for the treatment of various diseases, including malaria and a range of connective tissue disorders. Chloroquine retinopathy is an important complication that may appear even years after cessation of the drug, presenting with impaired visual acuity, central vision loss and progressive damage that could result in irreversible blindness. A detailed patient. Hydroxychloroquine retinopathy, it is important you ask your GP or specialist to refer you for screening. Progression of retinopathy. In most cases it is expected that stopping the hydroxychloroquine treatment will stop the. retinopathy worsening. If the condition does progress, a person may. experience significant loss of vision over time. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Treatment of hydroxychloroquine retinopathy Toxic Retinopathy With Hydroxychloroquine Therapy, Chloroquine Retinopathy Symptoms, Diagnosis and Treatment - Symptoma Chloroquine tlr9 inhibitorChloroquine cyanideIs plaquenil porcine basedReducing plaquenil dosagePlaquenil visual field screening May 16, 2011 Hydroxychloroquine Plaquenil; HCQ has been an important and effective drug for the treatment of lupus erythematosus and related autoimmune and inflammatory diseases for half a century, although its potential to cause retinal damage continues to raise concern among rheumatologists and ophthalmologists. Hydroxychloroquine Retinopathy Still Alive and Well - The.. Eye screening for patients taking hydroxychloroquine Plaquenil®. Retinal Physician - Hydroxychloroquine Maculopathy An Update on.. Hydroxychloroquine Plaquenil; HCQ has been an important and effective drug for the treatment of lupus erythematosus and related autoimmune and inflammatory diseases for half a century, although its potential to cause retinal damage continues to raise concern among rheumatologists and ophthalmologists. These two cases demonstrate that peripheral retinopathy, as well as maculopathy, can develop in patients who are treated with hydroxychloroquine for systemic lupus erythematosus, and that retinal function may remain stable after discontinuation of hydroxychloroquine treatment. PMID 1951589 Indexed for MEDLINE Publication Types Case Reports Aug 30, 2011 Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1.