Plaquenil and sle

Discussion in 'Chloroquin' started by el_aspect, 27-Feb-2020.

  1. krylov User

    Plaquenil and sle


    It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc.

    Hydroxychloroquine sulphate Plaquenil hair growth Hydroxychloroquine manufacturer not work Dosage for plaquenil

    Women with rheumatic diseases, including inflammatory arthritis and systemic lupus erythematosus SLE, fare better in pregnancy when their disease is under good control1,2. The role of hydroxychloroquine HCQ for achieving this control is now recognized. Several studies demonstrate that patients with SLE who continue HCQ during pregnancy have decreased flares and improved pregnancy outcomes. Systemic lupus erythematosus SLE is a chronic, autoimmune, inflammatory disease characterized by the presence of a plethora of autoantibodies, immune complex formation, and multiple organ system involvement. Gastrointestinal GI manifestations are common in SLE patients, but acute pancreatitis is rare 1–6. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work.

    The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea.

    Plaquenil and sle

    Systemic Lupus Erythematosus Living With Lupus, Systemic-Lupus-Erythematosus-Related Acute Pancreatitis A.

  2. Plaquenil medication side effects
  3. How long does hydroxychloroquine take to work
  4. Physicians prescribe hydroxychloroquine to treat systemic lupus erythematosus SLE, and it has been shown to have anti-thrombotic effects in SLE patients. Although obvious reasons exist to believe hydroxychloroquine may be useful to treat APS, its use in APS patients remains controversial.

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    PLAQUENIL WARNING - please please just be careful if you try plaquenil. I am in the UK and was prescribed this on diagnosis last year, as the apparent first "safe" treatment we try here for SLE lupus. I don't wish to scare anyone but just be alert for side effects! as I began to react after two tablets. Medical use. Hydroxychloroquine treats malaria, systemic lupus erythematosus, rheumatic disorders like rheumatoid arthritis, porphyria cutanea tarda, and Q fever. In 2014, its efficacy to treat Sjögren syndrome was questioned in a double-blind study involving 120 patients over a 48-week period. Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more.

     
  5. GDR2 Well-Known Member

    Rheumatoid arthritis can be difficult to diagnose in its early stages because the early signs and symptoms mimic those of many other diseases. Plaquenil From Malaria Treatment to Managing Lupus, RA. RA Treatment What is the Safest Treatment for Rheumatoid. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.
     
  6. goldelotto Well-Known Member

    Dosing schedules not well established in children Case reports describe dosage regimens that are effective yet tolerated, such as 12.5 mg PO twice weekly over 2 yr in a child aged 4-6 yr, and 100 mg PO twice weekly over 5 months in a child aged 12 yr; mg/kg dosing not reported Hypersensitivity to chloroquine, 4-aminoquinolones Psoriasis, porphyria, retinal or visual field changes For prevention, may use proguanil concomitantly Shown to cause severe hypoglycemia including loss of consciousness that could be life-threatening in patients treated with or without antidiabetic medications; patients should be warned about risk of hypoglycemia and associated clinical signs and symptoms; patients presenting with clinical symptoms suggestive of hypoglycemia during treatment with chloroquine should have blood glucose level checked and treatment reviewed as necessary Not effective in most areas; CDC recommends mefloquine or atovaquone/proguanil - check CDC traveler information for specific recommendations for region May cause hemolysis in glucose-6 phosphate dehydrogenase (G-6-PD) deficiency; blood monitoring may be needed as hemolytic anemia may occur, in particular in association with other drugs that cause hemolysis Monitor CBC periodically with prolonged therapy Caution with history of auditory damage Caution with hepatic disease, alcoholism, and coadministration with other hepatotoxic drugs May provoke seizures in patients with history of epilepsy Antacids and kaolin reduce chloroquine absorption; separate administration by at least 4 hr Irreversible retinal damage observed in some patients; significant risk factors for retinal damage include daily doses of chloroquine phosphate 2.3 mg/kg of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some concomitant drug products such as tamoxifen citrate, and concurrent macular disease A baseline ophthalmological examination should be performed within the first year of initiating therapy; for individuals with significant risk factors, monitoring should include annual examinations; discontinue if ocular toxicity is suspected; patient should be closely observed given that retinal changes (and visual disturbances) may progress even after cessation of therapy In individuals of Asian descent, retinal toxicity may first be noticed outside macula; it is recommended that visual field testing be performed in visual field of central 24 degrees instead of central 10 degrees May exacerbate heart failure Not effective against chloroquine- or hydroxychloroquine-resistant strains of Plasmodium species; information regarding geographic areas where resistance to chloroquine occurs, is available at the Centers for Disease Control and Prevention (gov/malaria) Does not treat hypnozoite liver stage forms of Plasmodium and will therefore not prevent relapses of malaria due to P. ovale; additional treatment with an anti-malarial agent active against these forms, such as an 8-aminoquinoline, is required for the treatment of infections with P. ovale Cases of cardiomyopathy resulting in cardiac failure, in some cases with fatal outcome, reported during long term therapy at high doses; monitor for signs and symptoms of cardiomyopathy and discontinue chloroquine if cardiomyopathy develops; chronic toxicity should be considered when conduction disorders (bundle branch block / atrio-ventricular heart block) diagnosed; if cardiotoxicity suspected, prompt therapy discontinuation may prevent life-threatening complications QT interval prolongation, torsades de pointes, and ventricular arrhythmias reported; risk is greater if chloroquine is administered at high doses; fatal cases reported; use with caution in patients with cardiac disease, a history of ventricular arrhythmias, uncorrected hypokalemia and/or hypomagnesemia, or bradycardia ( There are no adequate and well-controlled studies evaluating the safety and efficacy of chloroquine in pregnant women; usage during pregnancy should be avoided except in prophylaxis or treatment of malaria when benefit outweighs potential risk to fetus Because of the potential for serious adverse reactions in nursing infants from chloroquine, a decision should be made whether to discontinue nursing or to discontinue drug, taking into account potential clinical benefit of drug to mother A: Generally acceptable. Individual plans may vary and formulary information changes. Guidelines for Treatment of Malaria in the United States. Aralen Chloroquine Uses, Dosage, Side Effects. Medicines for the Prevention of Malaria While Traveling - Chloroquine.
     
  7. inetwork User

    Hydroxychloroquine - Wikipedia Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda.

    Hydroxychloroquine information booklet - Versus Arthritis