If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female. Hydroxychloroquine cause bladder infections Taking plaquenil Fibromyalgia and hydroxychloroquine Is plaquenil an immunosuppressant medication Regarding the dosing of hydroxychloroquine, we advocate the use of a weight-based dosing regimen with a cap at 400 mg per day, except in the case of renal insufficiency, when the dose should be. SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. The current American Academy of Ophthalmology AAO guidelines, published in 2016, recommend a maximum daily hydroxychloroquine dose of ≤5.0 mg/kg of real weight. These guidelines were established to minimize the likelihood of permanent vision loss related to hydroxychloroquine retinopathy. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. Weight based dosing plaquenil Plaquenil Hydroxychloroquine - Side Effects, Dosage., ACR Actual-weight hydroxychloroquine dosing works in SLE. Does plaquenil help restore hair loss redditPlaquenil causing psoriasisGeneric plaquenil gg320Chloroquine mode of action malariaDose of hydroxychloroquine Discussion. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a patient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. Plaquenil Risk Calculators. Hydroxychloroquine Plaquenil Dosing Calculator - MDCalc. Despite Plaquenil dosing recommendations, retinal toxicity.. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Adults— Standard dosing At first, 800 milligrams mg 4 tablets taken as a single dose. Then, 400 mg taken 6 hours, 24 hours, and 48 hours after the first dose. Weight-based dosing Dose is based on body weight and must be determined by your doctor. At first, 13 milligram mg per kilogram. Melton & Thomas describe the typical safe Plaquenil dosage this way The usual dosage is two 200mg tablets per day. This is generally a "safe" dose for patients having a lean body weight of at least 135 lbs. The generally-regarded safe dosage is 6.5mg/kg/qd, thus the 135 lb. safety threshold.