It says on the bottle I can’t take an antacid for at least four hours after taking the Plaquenil. I hate heart burn:( I take a PPI (proton pump inhibitor) essentially antacid in the morning that is supposed to last all day. I would ask your pharmacist first and see if it matters whether it is just a 'tums' or medication strength. I think if it keeps happening I’ll go talk to my pharmacist to see what they recommend. Has anyone else experienced heartburn while taking Plaquenil and if so what did you do to avoid or ease the heartburn? If they are not able to give you an answer your Family Dr or Rheumatoid will know. Fortunately the heartburn goes away after a few hours, but those few hours are very uncomfortable! Plaquenil lymph nodes Is hydroxychloroquine an immunosuppressant Plaquenil how to buy Is plaquenil A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Today on WebMD. Medications That Make You Tired. Drug interactions are reported among people who take Plaquenil and Famotidine together. This study is created by eHealthMe based on reports of 165 people who take Plaquenil and Famotidine from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from millions of FDA reports. Does Tums Interact with other Medications. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. But that's just the optimum way to take it, not the necessity. Sometimes what is suggested (no antacid for 4 hours) is not necessarily required if it means you can't or don't want to take your plaquenil anymore. the antacid will affect the absorption of the plaquenil and the amount your body can absorb. Can i take tums with plaquenil Hypothyroidism Can calcium supplements interfere with., Plaquenil and Famotidine drug interactions - eHealthMe Is hydroxychloroquine sulfate a blood thinner Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Avoid taking antacids within 4 hours of taking this medicine. It is best to separate these medicines by at least 4 hours. Do not cut, crush or chew this medicine. You can take it with or without food. If it upsets your stomach, take it with food. Hydroxychloroquine tablets. Tums Oral Interactions with Other Medication. Plaquenil & other drug interactions ? Lupus Forums at The.. Dec 18, 2007 Protect yourself You can simply take a break from Mevacor or Zocor if you need one of these specific antibiotics or antifungals, Horn says. Once your infection clears up and you're off those. Nausea and diarrhea This can often can be combatted by taking Plaquenil with food or milk. If you experience stomach upset while taking generic hydroxychloroquine, ask your doctor about trying name-brand Plaquenil instead. I had to start taking Tums for the Calcium in combination with Fosamax. The pharmacist told me to take it two hours before or after the Plaquenil as it might interfere with the absorption of the Plaquenil. Has anyone else been told this? I do know antiacid meds can affect the absorption of other meds.