Part of that is due to less exercise, part due to having no appetite thus feeling like anything I can get down is ok. Well, now I've been exercising at almost my pre-Lupus rate (ran a marathon a year before), eating a more moderate diet (clean protein, vegs & fruits), and am no longer taking that weight & bloat causing Prednisone (off Pred almost 2 yrs now). My question: Do you feel like you've gained weight on Plaquenil (ie without Prednisone)? Plaquenil and dental work Plaquenil localized scleroderma Hydroxychloroquine sulfate for lupus time usage If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. If you're on steroids that can be whats causing you to gain weight. I can't offer any advice on losing the weight if you come off the Plaquenil. Like Joy said, Plaquenil is the first medication they use in treating lupus. It has the least amount of side effects and seems to work well for most patients. This study is created by eHealthMe based on reports of 11,813 people who have side effects when taking Hydroxychloroquine sulfate from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. The results are personalized to your gender and age 0. My Lupus has been really quiet for about 2 yrs, and I'm afraid to change anything. The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Hydroxychloroquine side effects weight gain Plaquenil Side Effects Common, Severe, Long Term -, Plaquenil and weight gain - Chloroquine for research While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications. Protecting your eyesight when taking Plaquenil Lupus.. Will you have Weight increased with Hydroxychloroquine sulfate - eHealthMe. Medrol, Plaquenil and weight gain - Sclero Forums MAIN.. My question Do you feel like you've gained weight on Plaquenil ie without Prednisone? The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. What's happened with you? My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Our Plaquenil hydroxychloroquine Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.