My rheumatologist is running tests but thinks I have a mixed connective tissue disease. I noticed plaquenil helping with my fatigue more so than anything else. I just want some relief from the knee, shoulder and wrist pain. It does help my joint pain but I need extra help from other meds too It can take up to 6 months to get in your system and fully work, each person is different. Hydroxychloroquine retinopathy Plaquenil throat pain Plaquenil arthritis treatment Plaquenil hydroxychloroquine "been taking Plaquenil for RA for around 6 months then about 3 weeks ago started having muscular pain, not as bad as the joint pain I used to have but enough to be concerned. muscle weakness, painful, as if I worked out for 2 hours praying it is a dosage problem" Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory pathways. Check the latest outcomes from 53,829 Plaquenil users, or browse all drugs. What is Osteoarthritis? Osteoarthritis a joint disease caused by cartilage loss in a joint has been reported by people with osteoporosis, rheumatoid arthritis, high blood pressure, osteopenia, pain. If it does not help the joint pain be sure to talk to your doctor, there are other meds they can give you to help. From what I understand, it is "the first line of defense" and definitely worth a try! I pray it doesn't take that long for you to get some relief. Plaquenil was great for the pain and swelling but did almost nothing for the fatigue. Of all the meds, Plaquenil was the best for me and helped the most, but some people don't tolerate it. Plaquenil helps joint pain Does Plaquenil help with Joint Pain? - Autoimmune diseases., Taking Plaquenil for Rheumatoid Arthritis Mctd and plaquenilCan plaquenil cause joint pain Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites. Plaquenil belongs in a class of medications known as disease-modifying. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. How effective is Plaquenil for Osteoarthritis by duration.. Does Plaquenil help with Joint Pain? - Autoimmune diseases - Inspire. Joint pain is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Nov 28, 2010 This "dendritic deactivation" I made that phrase up helps reduce your immune system being silly and inflaming your joints. My sister was dx'd with Inflammatory Arthritis and Plaquenil sent her into remission some years ago now. Though it's my personal opinion that she actually has Psoriatic Arthritis and a Rheumy of limited intellect!