In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Hydroxychloroquine mechanism rheumatoid arthritis Alternative to plaquenil for ra Desethyl hydroxychloroquine Side effects. In some people, HCQ may cause gastrointestinal problems, such as nausea, vomiting, upset stomach, cramps, or diarrhea. These may occur for the first few days a person takes the drug while the body adjusts to the medication. Loss of appetite, tiredness, weakness, or headache are uncommon side effects and typically go away over time. It took many months for the ulcer like spots to go away but the drug works. In January 2018, I no longer had insurance so I dropped back down to 200 mg. It also took away most of my OA pain in my knees and hands. The only side effect taking the drug for me was severe burning mouth syndrome, ringing in the ears and an overall dryness. For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Plaquenil side effects go away Plaquenil Hydroxychloroquine - Side Effects, Dosage., Plaquenil Drug and Medication User Reviews on RxList Chloroquine and ambien May 07, 2012 Plaquenil is used in the treatment of sarcoidosis but its main use is in the treatment of malaria. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially field of vision tests need to be done every six months. Plaquenil Withdrawal – Life As An Anomaly. Hydroxychloroquine Side Effects Common, Severe, Long Term -. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Many people using this medication do not have serious side your doctor immediately if any of these unlikely but serious side effects occur arm/leg/back pain, fast heartbeat, hair loss/color change, mental/mood changes e.g. anxiety, depression, hallucinations, ringing in the ears/hearing loss, worsening of skin conditions e.g. psoriasismedication may infrequently cause serious sometimes permanent eye problems or muscle damage, especially if you take it for a long time. This can be a normal side effect from the plaquenil and it usually lasts a couple of weeks until your body adjusts to it. Try to stick it out, continue taking the compazine but know that that med itself causes drowsiness. You may want to ask for Zofran which doesnt make you as you take it before bed. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs.