Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and muscle relaxor Plaquenil-induced macular degeneration Chloroquine take how long to work Hydroxychloroquine HCQ-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy 1. A 32-year-old woman presented with a 1.5-year history of symmetric polyarthritis, positive rheumatoid factor, and anticyclic citrullinated peptide antibody, without erosive joint changes. Drug-Induced Hyperpigmentation caused by Plaquenil Hydroxychloroquine Plaquenil Hydroxycholoroquine Side Effects. Dermatologic side effects have included mucocutaneous hyperpigmentation, nonlight-sensitive psoriasis, bleaching of hair, alopecia, pruritus, photosensitivity, and skin eruptions such as urticarial, morbilliform, lichenoid, maculopapular, purpuric, erythema annulare centrifugum, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, and exfoliative dermatitis. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil hydroxychloroquine hyperpigmentation Hydroxychloroquine-Associated Hyperpigmentation Mimicking., Systemic Scleroderma Skin Involvement Hyperpigmentation and. Does plaquenil affect sexChloroquine phosphate medicine One of the potential long-term side-effects of using anti-malarial medications such as hydroxychloroquine Plaquenil, chloroquine, and quinacrine is the development of dark-colored patches on the skin. They often appear brown, black, or black and blue and tend to develop on the legs, especially around the shins. Hydroxychloroquine and skin darkening Hi All. - LUPUS UK. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Will you have Skin hyperpigmentation with Plaquenil - eHealthMe. Sep 13, 2019 Applies to hydroxychloroquine oral tablet Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Annular atrophic lichen planus AALP is a rare variant of lichen planus. The clinical presentation of AALP shows distinct atrophic plaques with elevated borders on the trunk and extremities. Histopathologic findings generally reveal a lichenoid dermatitis in active lesions with a distinct loss of elastic fibers in the center of the lesions. Feb 19, 2020 Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration.